RIP1 kinase inhibitor 4 is a selective inhibitor of RIP1 kinase with an EC50 of less than 100 nM, demonstrating the ability to penetrate the blood-brain barrier. This compound is pertinent for research into necrosis-related diseases, aiding in the investigation of cell programming mechanisms. Additionally, RIP1 kinase inhibitor 4 features an alkyne group, making it suitable for click chemistry applications, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
RIP1 kinase inhibitor 4 is a selective inhibitor of RIP1 kinase with an EC50 of less than 100 nM, demonstrating the ability to penetrate the blood-brain barrier. This compound is pertinent for research into necrosis-related diseases, aiding in the investigation of cell programming mechanisms. Additionally, RIP1 kinase inhibitor 4 features an alkyne group, making it suitable for click chemistry applications, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
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