Ripasudil

Name: Ripasudil
SKU: A15888
Price: 1015 CNY
Rating: 5 (1 reviews)

目录号: A15888

ROCK 抑制剂

1 篇发表文献

Ripasudil (K-115) 是一种强效的 ROCK 抑制剂，其 IC50 分别为 51 nM 和 19 nM，针对 ROCK1 和 ROCK2，用于治疗青光眼和眼压过高。

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Grouped product items
规格	价格	库存
5mg	¥1,015.00	现货
10mg	¥1,715.00	现货
25mg	¥3,465.00	现货
50mg	¥5,600.00	现货
100mg	¥8,400.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Ripasudil发表的1篇文献

Tilahun Ayane Debele, .et al. , Transl Vis Sci Technol, 2023, Dec; 12(12): 4 PMID: 38051267

生物活性

Discription

Ripasudil (K-115) is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.

Targets

Target	Value

产品信息

目录号	A15888
分子式	C15H23ClFN3O4S
分子量	395.88
CAS号	887375-67-9
SMILES	CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F.O.O.Cl
其他名称	K 115, K115, K-115
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 25 mg/mL (63.14 mM)
	Water	76 mg/mL (191.97 mM)
	Ethanol	Warmed: 5 mg/mL (12.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.26 mL	126.3 mL	252.6 mL
0.5 mM	5.05 mL	25.26 mL	50.52 mL
1 mM	2.53 mL	12.63 mL	25.26 mL
5 mM	0.51 mL	2.53 mL	5.05 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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