Ripasudil

目录号: A15888

ROCK inhibitor

Ripasudil

Ripasudil Chemical Structure

CAS NO. 887375-67-9

Ripasudil (K-115) is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,500.00
25 mg
¥ 5,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Ripasudil (K-115) is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.
靶点信息
ROCK2 ROCK1
19 nM51 nM
In vitro DMSO Warmed: 25 mg/mL (63.14 mM)
Water 76 mg/mL (191.97 mM)
Ethanol Warmed: 5 mg/mL (12.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.26 mL 126.3 mL 252.6 mL
0.5 mM 5.05 mL 25.26 mL 50.52 mL
1 mM 2.53 mL 12.63 mL 25.26 mL
5 mM 0.51 mL 2.53 mL 5.05 mL

*The above data is based on the productmolecular weight 395.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15888
作用机制 Inhibitor (抑制剂)
M. Wt 395.88
Formula C15H23ClFN3O4S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 887375-67-9
Synonyms K 115, K115, K-115
SMILES CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F.O.O.Cl

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