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RIPK1-IN-4

目录号: A21029
RIP1 kinase 抑制剂
RIPK1-IN-4(化合物8)是一种强效且选择性的II型激酶抑制剂,针对受体相互作用蛋白1(RIP1)激酶,并与RIP1的DLG-out非活性形式结合,其半抑制浓度(IC50s)分别为16 nM和10 nM,针对RIP1ADP-Glo激酶
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规格 价格 库存 数量
1mg
¥245.00
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5mg
¥665.00
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10mg
¥1,085.00
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25mg
¥1,855.00
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50mg
¥2,625.00
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100mg
¥3,570.00
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10mM * 1mL in DMSO
¥595.00
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生物活性
Discription RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A21029
分子式 C23H23N5O2
分子量 401.46
CAS号 1481641-08-0
SMILES CC(C)(C1=CC(NC(NC2=CC=C(C3=CC=CC4=C3C=CN=C4N)C=C2)=O)=NO1)C
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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