RIPK1-IN-4
目录号: A21029
RIP1 kinase 抑制剂
RIPK1-IN-4(化合物8)是一种强效且选择性的II型激酶抑制剂,针对受体相互作用蛋白1(RIP1)激酶,并与RIP1的DLG-out非活性形式结合,其半抑制浓度(IC50s)分别为16 nM和10 nM,针对RIP1和ADP-Glo激酶。
Discription | RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase. | |||||
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Cell Research |
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目录号 | A21029 |
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分子式 | C23H23N5O2 |
分子量 | 401.46 |
CAS号 | 1481641-08-0 |
SMILES | CC(C)(C1=CC(NC(NC2=CC=C(C3=CC=CC4=C3C=CN=C4N)C=C2)=O)=NO1)C |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2