RIPK1-IN-7
目录号: A18940
RIPK1 抑制剂
RIPK1-IN-7 是一种高效且选择性的 RIPK1 抑制剂,具有 4 nM 的 Kd 和 11 nM 的酶学 IC50。RIPK1-IN-7 在实验性 B16 黑色素瘤肺转移模型中表现出优异的 抗转移活性。
Discription | RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model. | |||||
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Cell Research |
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目录号 | A18940 |
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分子式 | C25H22F3N5O2 |
分子量 | 481.47 |
CAS号 | 2300982-44-7 |
SMILES | NC1=C2C(N(CC)C=C2C3=CC(CCN4C(CC5=CC=CC(OC(F)(F)F)=C5)=O)=C4C=C3)=NC=N1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2