Ripretinib
目录号: A19508
KIT and PDGFRA switch-control 抑制剂
Ripretinib（DCC-2618）是一种口服生物利用度高的，选择性的 KIT 和 PDGFRA 开关控制抑制剂。
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生物活性
| Discription | Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. | |||||
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| Cell Research |
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产品信息
| 目录号 | A19508 |
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| 分子式 | C24H21BrFN5O2 |
| 分子量 | 510.36 |
| CAS号 | 1442472-39-0 |
| SMILES | O=C(NC1=CC(C2=CC3=C(C=C(NC)N=C3)N(CC)C2=O)=C(Br)C=C1F)NC4=CC=CC=C4 |
| 其他名称 | DCC-2618, DCC2618, DCC 2618 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 89 mg/mL (174.39 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.59 mL | 97.97 mL | 195.94 mL |
| 0.5 mM | 3.92 mL | 19.59 mL | 39.19 mL |
| 1 mM | 1.96 mL | 9.8 mL | 19.59 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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