Risdiplam
目录号: A20300
SMN2 pre-mRNA splicing modifier
Risdiplam (RG7916; RO7034067) 是一种口服给药的、在中枢和周围分布的 SMN2 前体mRNA剪接修饰剂，它能增加存活运动神经元（SMN）蛋白水平。
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生物活性
| Discription | Risdiplam (RG7916; RO7034067) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels. |
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产品信息
| 目录号 | A20300 |
|---|---|
| 分子式 | C22H23N7O |
| 分子量 | 401.46 |
| CAS号 | 1825352-65-5 |
| SMILES | O=C(C=C(C(C=C1C)=NN2C1=NC(C)=C2)N=C3C=C4)N3C=C4N(CCN5)CC65CC6 |
| 其他名称 | RG7916; RO7034067 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Insoluble | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.91 mL | 124.55 mL | 249.09 mL |
| 0.5 mM | 4.98 mL | 24.91 mL | 49.82 mL |
| 1 mM | 2.49 mL | 12.45 mL | 24.91 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1825352-65-5 | 1825352-65-5 供应商 | 1825352-65-5 花费 | 1825352-65-5 生产商 | 订购 1825352-65-5 | 1825352-65-5 代理商