Ritonavir

目录号: A10799

HIV Protease inhibitor

Ritonavir

Ritonavir Chemical Structure

CAS NO. 155213-67-5

Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease.Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 800.00
50 mg
¥ 1,100.00
100 mg
¥ 1,500.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease.Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Targets
CYP3A4 HIV
In vitro (25°C) DMSO 100 mg/mL (138.7 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (4.16 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.87 mL 69.36 mL 138.72 mL
0.5 mM 2.77 mL 13.87 mL 27.74 mL
1 mM 1.39 mL 6.94 mL 13.87 mL
5 mM 0.28 mL 1.39 mL 2.77 mL

*The above data is based on the productmolecular weight 720.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10799
MECHANISM OF ACTION Inhibitor
M. Wt 720.9
Formula C37H48N6O5S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 155213-67-5
Synonyms Norvir, Norvir Softgel
SMILES CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O

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