Rivaroxaban (Xarelto)

Name: Rivaroxaban (Xarelto)
SKU: A10800

目录号: A10800

Factor Xa 抑制剂

Product Citations (3)

Rivaroxaban (Xarelto) Chemical Structure

CAS NO. 366789-02-8

Rivaroxaban (Xarelto)是一种Factor Xa的直接抑制剂，无细胞试验中Ki和IC50分别为0.4 nM和0.7 nM。

库存：现货

规格	价格	数量
5 mg	￥ 550.00
10 mg	￥ 750.00
50 mg	￥ 1,300.00
10mM * 1mL in DMSO	￥ 600.00

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生物活性

Rivaroxaban (Xarelto)是一种Factor Xa的直接抑制剂，无细胞试验中Ki和IC50分别为0.4 nM和0.7 nM。

靶点信息

Factor Xa (Cell-free assay)	Prothrombinase (Cell-free assay)
0.7 nM	2.1 nM

溶解度 *

In vitro (25°C)	DMSO	83 mg/mL (190.41 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose+0.2% Tween 80	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.94 mL	114.71 mL	229.41 mL
0.5 mM	4.59 mL	22.94 mL	45.88 mL
1 mM	2.29 mL	11.47 mL	22.94 mL
5 mM	0.46 mL	2.29 mL	4.59 mL

*The above data is based on the productmolecular weight 435.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10800
作用机制	Inhibitor (抑制剂)
M. Wt	435.9
Formula	C19H18ClN3O5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	366789-02-8
Synonyms	BAY 59-7939, Xarelto
SMILES	C1COCC(=O)N1C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl