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产品目录号: A13067


产品名 目录号 价格 数量
RKI-1447 5mg A13067-5
¥ 800.00
RKI-1447 10mg A13067-10
¥ 1,200.00
RKI-1447 25mg A13067-25
¥ 2,400.00
RKI-1447 50mg A13067-50
¥ 4,400.00
RKI-1447 10mM * 1mL in DMSO A13067-10mM-D
¥ 1,110.00



RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A13067
Mechanism of action Inhibitor
分子量 326.37
化学分子式 C16H14N4O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1342278-01-6
Synonyms RKI1447; RKI 1447. ROCK Inhibitor XIII
SMILES code C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3
化学名称 1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea


RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.
6.2 nM14.5 nM


Solubility (25°C) * In vitro DMSO 65 mg/mL (199.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.64 mL 153.2 mL 306.4mL
0.5 mM 6.13 mL 30.64 mL 61.28 mL
1 mM 3.06 mL 15.32 mL 30.64 mL
5 mM 0.61 mL 3.06 mL 6.13 mL

*The above data is based on the productmolecular weight 326.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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