RKI-1447
目录号: A13067
ROCK1/ROCK2 抑制剂
RKI-1447 是一种强效的 Rho-associated ROCK kinases 抑制剂，在乳腺癌中具有抗侵袭和抗肿瘤活性。
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生物活性
| Discription | RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. | ||
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产品信息
| 目录号 | A13067 |
|---|---|
| 分子式 | C16H14N4O2S |
| 分子量 | 326.37 |
| CAS号 | 1342278-01-6 |
| SMILES | C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3 |
| 其他名称 | RKI1447; RKI 1447. ROCK Inhibitor XIII |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 62 mg/mL (189.97 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 15% Captisol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.64 mL | 153.2 mL | 306.4 mL |
| 0.5 mM | 6.13 mL | 30.64 mL | 61.28 mL |
| 1 mM | 3.06 mL | 15.32 mL | 30.64 mL |
| 5 mM | 0.61 mL | 3.06 mL | 6.13 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1342278-01-6 | 1342278-01-6 供应商 | 1342278-01-6 花费 | 1342278-01-6 生产商 | 订购 1342278-01-6 | 1342278-01-6 代理商