RN-1734

Name: RN-1734
SKU: A20616
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A20616

TRPV4 拮抗剂

RN-1734 是 TRPV4 通道的选择性拮抗剂，完全拮抗 4αPDD 介导的 TRPV4 激活，对所有三种物种具有相当的低微摩尔 IC50 值（hTRPV4：2.3 μM，mTRPV4：5.9 μM，rTRPV4：3.2 μM）。

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Grouped product items
规格	价格	库存
5mg	¥140.00	现货
10mg	¥245.00	现货
25mg	¥525.00	现货
50mg	¥875.00	现货
100mg	¥1,400.00	现货
200mg	¥2,030.00	现货
*10mM 1mL in DMSO**	¥140.00	现货
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Data Sheet

SDS

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生物活性

Discription

RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM).

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20616
分子式	C14H22Cl2N2O2S
分子量	353.31
CAS号	946387-07-1
SMILES	O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O
其他名称	RN1734, RN 1734
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	63 mg/mL (178.31 mM)
	Water	Insoluble
	Ethanol	63 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.3 mL	141.52 mL	283.04 mL
0.5 mM	5.66 mL	28.3 mL	56.61 mL
1 mM	2.83 mL	14.15 mL	28.3 mL
5 mM	0.57 mL	2.83 mL	5.66 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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