Ro 3306

目录号: A14437

CDK1 inhibitor

Ro 3306

Ro 3306 Chemical Structure

CAS NO. 872573-93-8

Ro 3306 is an ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively).

库存: 现货

规格 价格 数量
10 mg
¥ 1,000.00
25 mg
¥ 1,800.00
50 mg
¥ 3,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Ro 3306 is an ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively).
Targets
Target Value
CDK1ki: 20nM
PKCδki: 318nM
SGKki: 497nM
ERKki: 1980nM
PKAki: >2000nM
Aktki: >2000nM
PKCαki: >2000nM
Fynki: >2000nM
EphB3ki: >2000nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.45 mL 142.27 mL 284.54 mL
0.5 mM 5.69 mL 28.45 mL 56.91 mL
1 mM 2.85 mL 14.23 mL 28.45 mL
5 mM 0.57 mL 2.85 mL 5.69 mL

*The above data is based on the productmolecular weight 351.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14437
MECHANISM OF ACTION Inhibitor
M. Wt 351.45
Formula C18H13N3OS2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 872573-93-8
Synonyms Ro3306, Ro-3306
SMILES C1=CC2=C(C=CC(=C2)/C=C/3\C(=O)N=C(S3)NCC4=CC=CS4)N=C1

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