Ro 48-8071 fumarate
目录号: A14321
Ro 48-8071 在2,3-氧化角鲨烯环化酶(OSC)水平抑制胆固醇生物合成。它在纳摩尔范围内阻断 HepG2 细胞中的 OSC 和胆固醇合成。一种新型降脂剂。
| Discription | Ro 48-8071 inhibits cholesterol biosynthesis at the level of 2,3-oxidosqualene cyclase (OSC). It blocks OSC and cholesterol synthesis in HepG2 cells in the nanomolar range. A novel lipid lowering agent. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
|
| 目录号 | A14321 |
|---|---|
| 分子式 | C23H27NO2BrF.C4H4O4 |
| 分子量 | 564.4 |
| CAS号 | 189197-69-1 |
| SMILES | CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C.C(=C/C(=O)O)\C(=O)O |
| 其他名称 | Ro 488071, Ro488071 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2