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Ro 48-8071是OSC（氧化角鲨烯环化酶；IC50 = 6.5 nM）的抑制剂，具有低密度脂蛋白（LDL）胆固醇降低活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.3 mL | 111.52 mL | 223.03 mL |
| 0.5 mM | 4.46 mL | 22.3 mL | 44.61 mL |
| 1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
*The above data is based on the productmolecular weight 448.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14203 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 448.37 |
| Formula | C23H27BrFNO2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 161582-11-2 |
| Synonyms | Ro-48-8071, Ro48-8071 |
| SMILES | CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C |
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