RO-5963
目录号: A18813
MDM2/MDMX 抑制剂
RO-5963 是一种抑制剂,能够抑制 MDM2 和 MDMX 与 p53 的相互作用,其半抑制浓度(IC50)分别约为 17 nM 和 24 nM。
Discription | RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53 with IC50s of ~17 nM and ~24 nM, respectively. |
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目录号 | A18813 |
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分子式 | C24H21ClF2N4O5 |
分子量 | 518.9 |
CAS号 | 1416663-77-8 |
SMILES | O=C(NC(CO)CO)C(N(C(N/C1=C\C2=CNC3=C2C=CC(Cl)=C3C)=O)C1=O)C4=CC=C(F)C(F)=C4 |
其他名称 | RO-5963; RO 5963; RO5963; |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2