RO3280

目录号: A13245

PLK1 inhibitor

RO3280 Chemical Structure

CAS NO. 1062243-51-9

RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 4,000.00
50 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,890.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
In vitro DMSO 100 mg/mL (183.95 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (183.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.98 mL 183.96 mL
0.5 mM 3.68 mL 18.4 mL 36.79 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13245
MECHANISM OF ACTION Inhibitor
M. Wt 543.61
Formula C27H35F2N7O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1062243-51-9
Synonyms RO 3280, RO-3280
SMILES CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC

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