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RO4987655

MEK1 抑制剂

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产品目录号: A13272

库存状态:中国现货中国现货

产品名 目录号 价格 数量
RO4987655 5mg A13272-5
¥ 2,200.00
RO4987655 10mg A13272-10
¥ 3,800.00
RO4987655 25mg A13272-25
¥ 7,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity.

RO4987655

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Chemical Information

目录号 A13272
Mechanism of action Inhibitor
分子量 565.28
化学分子式 C20H19F3IN3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 874101-00-5
Synonyms RO-4987655, RO 4987655
SMILES code C1CC(=O)N(OC1)CC2=C(C(=C(C(=C2)C(=O)NOCCO)NC3=C(C=C(C=C3)I)F)F)F
化学名称 3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-5-((3-oxo-1,2-oxazinan-2-yl)methyl)benzamide

生物活性

Description
RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.69 mL 88.45 mL 176.9mL
0.5 mM 3.54 mL 17.69 mL 35.38 mL
1 mM 1.77 mL 8.85 mL 17.69 mL
5 mM 0.35 mL 1.77 mL 3.54 mL

*The above data is based on the productmolecular weight 565.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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