Roblitinib

Name: Roblitinib
SKU: A19431

目录号: A19431

FGFR4 inhibitor

Roblitinib Chemical Structure

CAS NO. 1708971-55-4

Roblitinib (FGF-401; Compound Example 83) is a highly selective and potent FGFR4 inhibitor with an IC50 of 1.9 nM. Roblitinib has antitumor activity.

库存：现货

规格	价格	数量
2 mg	￥ 800.00
5 mg	￥ 1,200.00
10 mg	￥ 2,000.00
50 mg	￥ 6,000.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Roblitinib (FGF-401; Compound Example 83) is a highly selective and potent FGFR4 inhibitor with an IC50 of 1.9 nM. Roblitinib has antitumor activity.

溶解度 *

In vitro	DMSO	5 mg/mL (9.87 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (3.94 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.74 mL	98.7 mL	197.41 mL
0.5 mM	3.95 mL	19.74 mL	39.48 mL
1 mM	1.97 mL	9.87 mL	19.74 mL
5 mM	0.39 mL	1.97 mL	3.95 mL

*The above data is based on the productmolecular weight 506.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19431
作用机制	Inhibitor (抑制剂)
M. Wt	506.56
Formula	C25H30N8O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1708971-55-4
Synonyms	FGF-401, FGF401, FGF 401
SMILES	CN1CC(N(CC2=CC(CCCN3C(NC4=CC(NCCOC)=C(C#N)C=N4)=O)=C3N=C2C=O)CC1)=O