ROC-325
目录号: A17031
Autophagy 抑制剂
ROC-325 是一种自噬抑制剂。与现有的自噬抑制剂羟氯喹（HCQ）相比，ROC-325 在 12 种具有不同遗传背景的癌症细胞系中展示了更优越的 体外抗癌效果。
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生物活性
| Discription | ROC-325 is an autophagy inhibitor. ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds. |
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产品信息
| 目录号 | A17031 |
|---|---|
| 分子式 | C28H27ClN4OS |
| 分子量 | 503.06 |
| CAS号 | 1859141-26-6 |
| SMILES | O=C1C2=C(C(C)=CC=C2NCCN(C)CCNC3=C(C=CC(Cl)=C4)C4=NC=C3)SC5=CC=CC=C51 |
| 其他名称 | ROC 325, ROC325 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 3 mg/mL (5.96 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (5.96 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.88 mL | 99.39 mL | 198.78 mL |
| 0.5 mM | 3.98 mL | 19.88 mL | 39.76 mL |
| 1 mM | 1.99 mL | 9.94 mL | 19.88 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.98 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 ROC-325 | ROC-325 供应商 | ROC-325 花费 | ROC-325 生产商 | 订购 ROC-325 | ROC-325 代理商
| 购买 1859141-26-6 | 1859141-26-6 供应商 | 1859141-26-6 花费 | 1859141-26-6 生产商 | 订购 1859141-26-6 | 1859141-26-6 代理商