Rofecoxib (Vioxx)
目录号: A11918
COX-2 抑制剂
Rofecoxib(Vioxx)是一种 COX-2 抑制剂,其 IC50 为 18 nM。
| Discription | Rofecoxib (Vioxx) is a COX-2 inhibitor with IC50 of 18 nM. | |||||
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| Cell Research |
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| 目录号 | A11918 |
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| 分子式 | C17H14O4S |
| 分子量 | 314.35 |
| CAS号 | 162011-90-7 |
| SMILES | CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3 |
| 其他名称 | Vioxx |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 62 mg/mL (197.22 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.81 mL | 159.06 mL | 318.12 mL |
| 0.5 mM | 6.36 mL | 31.81 mL | 63.62 mL |
| 1 mM | 3.18 mL | 15.91 mL | 31.81 mL |
| 5 mM | 0.64 mL | 3.18 mL | 6.36 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2