Rosopatamab (HuJ591) is a humanized IgG1 monoclonal antibody targeting the Prostate-Specific Membrane Antigen (PSMA). This antibody is specifically designed for use in cancer research, with a particular focus on prostate cancer. Rosopatamab can be conjugated to lutetium-177 (177Lu), a low-energy beta-emitting radioisotope, via the bifunctional chelator DOTA-NHS ester. This conjugation facilitates the creation of a radioimmunoconjugate that selectively targets and efficiently eradicates malignant prostate cells. This specificity and efficiency make Rosopatamab an invaluable tool in the development of targeted radiotherapeutic strategies in oncology research.
Rosopatamab (HuJ591) is a humanized IgG1 monoclonal antibody targeting the Prostate-Specific Membrane Antigen (PSMA). This antibody is specifically designed for use in cancer research, with a particular focus on prostate cancer. Rosopatamab can be conjugated to lutetium-177 (177Lu), a low-energy beta-emitting radioisotope, via the bifunctional chelator DOTA-NHS ester. This conjugation facilitates the creation of a radioimmunoconjugate that selectively targets and efficiently eradicates malignant prostate cells. This specificity and efficiency make Rosopatamab an invaluable tool in the development of targeted radiotherapeutic strategies in oncology research.
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