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Rp-8-Br-PET-cGMPS

目录号: A16030
PKG 抑制剂
Rp-8-Br-PET-cGMPS 是一种代谢稳定的竞争性抑制剂,针对 cGKI(Ki = 30 nM)和 cGKII(cGMP依赖的蛋白激酶G),并且能阻断 cGMP门控的视网膜型离子通道(IC50 = 25 μM)。
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规格 价格 库存 数量
500µg
¥2,240.00
现货
1mg
¥3,780.00
现货
5mg
¥15,960.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Rp-8-Br-PET-cGMPS is metabolically stable, competitive inhibitor of cGKI (Ki = 30 nM) and cGKII (cGMP-dependent protein kinase G) and blocks cGMP-gated retinal type ion channels (IC50 = 25 μM).
产品信息
目录号 A16030
分子式 C18H14BrN5NaO6PS
分子量 562.27
CAS号 185246-32-6
SMILES C1C2C(C(C(O2)N3C4=C(C(=O)N5C=C(NC5=N4)C6=CC=CC=C6)N=C3Br)O)OP(=O)(O1)[S-].[Na+]
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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