Rp-8-Br-PET-cGMPS
目录号: A16030
PKG 抑制剂
Rp-8-Br-PET-cGMPS 是一种代谢稳定的竞争性抑制剂,针对 cGKI(Ki = 30 nM)和 cGKII(cGMP依赖的蛋白激酶G),并且能阻断 cGMP门控的视网膜型离子通道(IC50 = 25 μM)。
Discription | Rp-8-Br-PET-cGMPS is metabolically stable, competitive inhibitor of cGKI (Ki = 30 nM) and cGKII (cGMP-dependent protein kinase G) and blocks cGMP-gated retinal type ion channels (IC50 = 25 μM). |
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目录号 | A16030 |
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分子式 | C18H14BrN5NaO6PS |
分子量 | 562.27 |
CAS号 | 185246-32-6 |
SMILES | C1C2C(C(C(O2)N3C4=C(C(=O)N5C=C(NC5=N4)C6=CC=CC=C6)N=C3Br)O)OP(=O)(O1)[S-].[Na+] |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2