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RS 504393

CCR2 拮抗剂.

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产品目录号: A15227

库存状态:中国现货中国现货

产品名 目录号 价格 数量
RS 504393 10mg A15227-10
¥ 1,300.00
RS 504393 25mg A15227-25
¥ 2,400.00
RS 504393 50mg A15227-50
¥ 4,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 uM for inhibition of human recombinant CCR2b and CCR1 receptors respectively).

RS 504393

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Chemical Information

目录号 A15227
Mechanism of action Antagonist
分子量 417.5
化学分子式 C25H27N3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 300816-15-3
Synonyms RS-504393, RS504393
SMILES code CC1=CC2=C(C=C1)NC(=O)OC23CCN(CC3)CCC4=C(OC(=N4)C5=CC=CC=C5)C
化学名称 6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one

生物活性

Description
RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 uM for inhibition of human recombinant CCR2b and CCR1 receptors respectively).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.95 mL 119.76 mL 239.52mL
0.5 mM 4.79 mL 23.95 mL 47.9 mL
1 mM 2.4 mL 11.98 mL 23.95 mL
5 mM 0.48 mL 2.4 mL 4.79 mL

*The above data is based on the productmolecular weight 417.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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