RSL3

Name: RSL3
SKU: A15865
Price: 175 CNY
Rating: 5 (9 reviews)

目录号: A15865

Ferroptosis 抑制剂

9 篇发表文献

RSL3 是一种以 VDAC-独立方式激活 铁死亡 的化合物，对携带致癌 RAS 的肿瘤细胞表现出选择性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥455.00	现货
10mg	¥840.00	现货
25mg	¥1,645.00	现货
50mg	¥2,520.00	现货
100mg	¥3,325.00	现货
500mg	¥7,525.00	现货
1g	¥9,975.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用RSL3发表的9篇文献

Cheng Chen, .et al. , Neurochem Res, 2025, Mar 18;50(2):122 PMID: 40100474

Xiaona Cao, .et al. , J Nanobiotechnology, 2025, Feb 24;23(1):136 PMID: 39994619

Naoya Yamada, .et al. , Nat Commun, 2024, 15:2195

Ning Li, .et al. , J Ovarian Res, 2024, Feb 23;17(1):49 PMID: 38396022

Yuki Kojima, .et al. , Journal of Gastroenterology, 2023, Nov 10

Qingyu Zhang, .et al. , Cell Death Discov, 2023, Mar 8;9(1):83 PMID: 36882396

Sampilvanjil A, .et al. , Am J Physiol Heart Circ Physiol, 2020, Mar 1;318(3):H508-H518 PMID: 31975626

Fujiki K, .et al. , Cell Death Differ, 2019, Feb 25 PMID: 30804470

Samantha W. Alvarez, .et al. , Nature, 2017, Nov 30; 551(7682): 639-643 PMID: 29168506

生物活性

Discription

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15865
分子式	C23H21ClN2O5
分子量	440.88
CAS号	1219810-16-8
SMILES	COC(C1=CC=C([C@@]2([H])C3=C(C4=CC=CC=C4N3)C[C@](N2C(CCl)=O)([H])C(OC)=O)C=C1)=O
其他名称	1S,3R-RSL3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	82 mg/mL (185.99 mM)
	Water	Insoluble
	Ethanol	20 mg/mL
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.68 mL	113.41 mL	226.82 mL
0.5 mM	4.54 mL	22.68 mL	45.36 mL
1 mM	2.27 mL	11.34 mL	22.68 mL
5 mM	0.45 mL	2.27 mL	4.54 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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