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Ferroptosis 抑制剂

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产品目录号: A15865


产品名 目录号 价格 数量
RSL3 5mg A15865-5
¥ 1,200.00
RSL3 10mg A15865-10
¥ 2,100.00
RSL3 25mg A15865-25
¥ 4,500.00



RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 RSL3 发表的文献 (2)
  • Fujiki K, .et al. Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms, Cell Death Differ, 2019, Feb 25 PMID: 30804470
  • Samantha W. Alvarez, .et al. NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis, Nature, 2017, Nov 30; 551(7682): 639每643 PMID: 29168506

Chemical Information

目录号 A15865
Mechanism of action Inhibitor
分子量 440.88
化学分子式 C23H21ClN2O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1219810-16-8
Synonyms 1S,3R-RSL3
SMILES code COC(C1=CC=C([C@@]2([H])C3=C(C4=CC=CC=C4N3)C[C@](N2C(CCl)=O)([H])C(OC)=O)C=C1)=O
化学名称 1H-?Pyrido[3,?4-?b]?indole-?3-?carboxylic acid, 2-?(2-?chloroacetyl)?-?2,?3,?4,?9-?tetrahydro-?1-?[4-?(methoxycarbonyl)?phenyl]?-?, methyl ester, (1S,?3R)?-


RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.68 mL 113.41 mL 226.82mL
0.5 mM 4.54 mL 22.68 mL 45.36 mL
1 mM 2.27 mL 11.34 mL 22.68 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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