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RSL3

促销

Ferroptosis 抑制剂

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产品目录号: A15865

库存状态:中国现货中国现货

产品名 目录号 价格 数量
RSL3 5mg A15865-5
¥ 1,200.00
RSL3 10mg A15865-10
¥ 2,100.00
RSL3 25mg A15865-25
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.

RSL3

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 RSL3 发表的文献 (2)
  • Fujiki K, .et al. Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms, Cell Death Differ, 2019, Feb 25 PMID: 30804470
  • Samantha W. Alvarez, .et al. NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis, Nature, 2017, Nov 30; 551(7682): 639每643 PMID: 29168506

Chemical Information

目录号 A15865
Mechanism of action Inhibitor
分子量 440.88
化学分子式 C23H21ClN2O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1219810-16-8
Synonyms 1S,3R-RSL3
SMILES code COC(C1=CC=C([C@@]2([H])C3=C(C4=CC=CC=C4N3)C[C@](N2C(CCl)=O)([H])C(OC)=O)C=C1)=O
化学名称 1H-?Pyrido[3,?4-?b]?indole-?3-?carboxylic acid, 2-?(2-?chloroacetyl)?-?2,?3,?4,?9-?tetrahydro-?1-?[4-?(methoxycarbonyl)?phenyl]?-?, methyl ester, (1S,?3R)?-

生物活性

Description
RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
Targets
Gpx4

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.68 mL 113.41 mL 226.82mL
0.5 mM 4.54 mL 22.68 mL 45.36 mL
1 mM 2.27 mL 11.34 mL 22.68 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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