Omaveloxolone (RTA 408)

Name: Omaveloxolone (RTA 408)
SKU: A14417
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A14417

Nrf2 抑制剂

RTA-408 是一种合成三萜类化合物，能强效激活抗氧化转录因子 Nrf2 并抑制促炎症转录因子 NF-kB。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥560.00	现货
10mg	¥805.00	现货
25mg	¥1,505.00	现货
50mg	¥2,555.00	现货
100mg	¥3,710.00	现货
500mg	¥8,015.00	现货
*10mM 1mL in DMSO**	¥700.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-kB.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A14417
分子式	C33H44F2N2O3
分子量	554.71
CAS号	1474034-05-3
SMILES	C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)NC(=O)C(C)(F)F
其他名称	RTA 408, RTA408
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	98 mg/mL (176.66 mM)
	Water	Insoluble
	Ethanol	20 mg/mL (36.05 mM)
In vivo	10%DMSO+90% Corn oil	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.03 mL	90.14 mL	180.27 mL
0.5 mM	3.61 mL	18.03 mL	36.05 mL
1 mM	1.8 mL	9.01 mL	18.03 mL
5 mM	0.36 mL	1.8 mL	3.61 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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