RTA-408

目录号: A14417

Nrf2 抑制剂

RTA-408

RTA-408 Chemical Structure

CAS NO. 1474034-05-3

RTA-408是一种合成的三萜类化合物,可有效激活抗氧化转录因子Nrf2并抑制促炎转录因子NF-kB。

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,350.00
25 mg
¥ 2,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

RTA-408是一种合成的三萜类化合物,可有效激活抗氧化转录因子Nrf2并抑制促炎转录因子NF-kB。
靶点信息
Nrf2
In vitro (25°C) DMSO 98 mg/mL (176.66 mM)
Water Insoluble
Ethanol 20 mg/mL (36.05 mM)
In vivo 10%DMSO+90% Corn oil 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.03 mL 90.14 mL 180.27 mL
0.5 mM 3.61 mL 18.03 mL 36.05 mL
1 mM 1.8 mL 9.01 mL 18.03 mL
5 mM 0.36 mL 1.8 mL 3.61 mL

*The above data is based on the productmolecular weight 554.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14417
作用机制 Inhibitor (抑制剂)
M. Wt 554.71
Formula C33H44F2N2O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1474034-05-3
Synonyms RTA 408, RTA408
SMILES C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)NC(=O)C(C)(F)F

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