Runimotamab is a chimeric humanized antibody of the IgG1-?? isotype, designed to specifically target CD3E and HER2 receptors. This dual targeting strategy enhances the antibody's ability to mediate immune responses against cells expressing HER2, a receptor tyrosine kinase implicated in the progression of several forms of cancer, including breast and gastric cancers. Runimotamab's engagement of CD3E on T cells potentially facilitates a more direct and potent cytotoxic response, making it a valuable tool for research in cancer immunotherapy and the study of bispecific antibody mechanisms.
Runimotamab is a chimeric humanized antibody of the IgG1-?? isotype, designed to specifically target CD3E and HER2 receptors. This dual targeting strategy enhances the antibody's ability to mediate immune responses against cells expressing HER2, a receptor tyrosine kinase implicated in the progression of several forms of cancer, including breast and gastric cancers. Runimotamab's engagement of CD3E on T cells potentially facilitates a more direct and potent cytotoxic response, making it a valuable tool for research in cancer immunotherapy and the study of bispecific antibody mechanisms.
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