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Rupatadine Fumarate


PAFR 抑制剂/H1 receptor 抑制剂

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产品目录号: A12356


产品名 目录号 价格 数量
Rupatadine Fumarate 5mg A12356-5
¥ 600.00
Rupatadine Fumarate 10mg A12356-10
¥ 1,000.00
Rupatadine Fumarate 25mg A12356-25
¥ 2,000.00
Rupatadine Fumarate 50mg A12356-50
¥ 3,500.00



Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 and 102 nM, respectively.

Rupatadine Fumarate




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Chemical Information

目录号 A12356
Mechanism of action Inhibitor
分子量 532.03
化学分子式 C26H26ClN3.C4H4O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 182349-12-8
Synonyms N/A
SMILES code CC1=CC(=CN=C1)CN2CCC(=C3C4=C(CCC5=C3N=CC=C5)C=C(C=C4)Cl)CC2.C(=C/C(=O)O)\C(=O)O
化学名称 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine fumarate


Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 and 102 nM, respectively.
Histamine H1 receptor PAFR
102 nM(Ki)550 nM(Ki)


Solubility (25°C) * In vitro DMSO 9 mg/mL (16.91 mM)
Water <1 mg/mL (<1 mM)
Ethanol 13 mg/mL (24.43 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.8 mL 93.98 mL 187.96mL
0.5 mM 3.76 mL 18.8 mL 37.59 mL
1 mM 1.88 mL 9.4 mL 18.8 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 532.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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