(S)-10-Hydroxycamptothecin

目录号: A11997

Topoisomerase

(S)-10-Hydroxycamptothecin Chemical Structure

CAS NO. 19685-09-7

(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.

库存: 现货

规格 价格 数量
50 mg
¥ 600.00
100 mg
¥ 1,000.00
250 mg
¥ 2,000.00
500 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 630.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.
靶点信息
DNA topoisomerase I
In vitro (25°C) DMSO 8 mg/mL heating (21.95 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.45 mL 137.23 mL 274.46 mL
0.5 mM 5.49 mL 27.45 mL 54.89 mL
1 mM 2.74 mL 13.72 mL 27.45 mL
5 mM 0.55 mL 2.74 mL 5.49 mL

*The above data is based on the productmolecular weight 364.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11997
MECHANISM OF ACTION Inhibitor
M. Wt 364.35
Formula C20H16N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 19685-09-7
Synonyms HCPT;SN38;Ampule;NSC 107124;HYDROCAMPTOTHECINE;HYDROXYCAMPTOTHECIN;
SMILES CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O

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