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S-2474 is an inhibitor of COX-2 and 5-lipoxygenase (5-LO), with IC50s of 11 nM and 27 μM for COX-2 and COX-1 in human intact cells, and used as a nonsteroidal anti-inflammatory drug.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.36 mL | 136.79 mL | 273.58 mL |
| 0.5 mM | 5.47 mL | 27.36 mL | 54.72 mL |
| 1 mM | 2.74 mL | 13.68 mL | 27.36 mL |
| 5 mM | 0.55 mL | 2.74 mL | 5.47 mL |
*The above data is based on the productmolecular weight 365.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20699 |
|---|---|
| M. Wt | 365.53 |
| Formula | C20H31NO3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 158089-95-3 |
| Synonyms | S2474, S 2474 |
| SMILES | OC1=C(C(C)(C)C)C=C(/C=C2CCN(CC)S\2(=O)=O)C=C1C(C)(C)C |
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