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S/GSK1349572 (Dolutegravir)

目录号: A11068
HIV integrase 抑制剂
S/GSK1349572 是一种强效的下一代 HIV 整合酶抑制剂,并且通过 60 种整合酶突变分子克隆证实了其卓越的抗药性特性。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
2mg
¥245.00
现货
5mg
¥420.00
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10mg
¥770.00
现货
25mg
¥1,225.00
现货
50mg
¥1,960.00
现货
100mg
¥3,115.00
现货
200mg
¥4,410.00
现货
500mg
¥6,230.00
现货
1g
¥8,155.00
现货
10mM * 1mL in DMSO
¥385.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用S/GSK1349572 (Dolutegravir)发表的1篇文献
  • Lea El Khoury, .et al. , PeerJ Preprints, 2019, 7:e27833v1
  • 生物活性
    Discription S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A11068
    分子式 C20H19F2N3O5
    分子量 419.4
    CAS号 1051375-16-6
    SMILES C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
    其他名称 Dolutegravir, GSK-1349572
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO Warmed: 71 mg/mL (169.3 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.84 mL 119.22 mL 238.44 mL
    0.5 mM 4.77 mL 23.84 mL 47.69 mL
    1 mM 2.38 mL 11.92 mL 23.84 mL
    5 mM 0.48 mL 2.38 mL 4.77 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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