S/GSK1349572 (Dolutegravir)

目录号: A11068

HIV integrase inhibitor

S/GSK1349572 (Dolutegravir)

S/GSK1349572 (Dolutegravir) Chemical Structure

CAS NO. 1051375-16-6

S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
50 mg
¥ 5,800.00
100 mg
¥ 8,800.00
10mM * 1mL in DMSO
¥ 1,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.
Targets
HIV integrase (Cell-free assay)
2.7 nM
In vitro DMSO 83 mg/mL heating (197.91 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.22 mL 238.44 mL
0.5 mM 4.77 mL 23.84 mL 47.69 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11068
MECHANISM OF ACTION Inhibitor
M. Wt 419.4
Formula C20H19F2N3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1051375-16-6
Synonyms Dolutegravir, GSK-1349572
SMILES C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O

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