S107
目录号: A12716
S107 是一种选择性的 1,4-苯并噻二唑衍生物，通过增强 calstabin2 对突变和/或 PKA 磷酸化通道的结合亲和力，稳定 RyR2 通道。
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生物活性
| Discription | S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. | |||||
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| Cell Research |
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产品信息
| 目录号 | A12716 |
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| 分子式 | C11H15NOS |
| 分子量 | 209.31 |
| CAS号 | 927871-76-9 |
| SMILES | COC1=CC=C2C(CN(C)CCS2)=C1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 40 mg/mL (191.1 mM) | |
| Water | Insoluble | ||
| Ethanol | 40 mg/mL (191.1 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 47.78 mL | 238.88 mL | 477.76 mL |
| 0.5 mM | 9.56 mL | 47.78 mL | 95.55 mL |
| 1 mM | 4.78 mL | 23.89 mL | 47.78 mL |
| 5 mM | 0.96 mL | 4.78 mL | 9.56 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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