S3I-201 (NSC 74859)

目录号: A10817

Stat3 Inhibitor

S3I-201 (NSC 74859) Chemical Structure

CAS NO. 501919-59-1

S3I-201 (NSC 74859) is a novel inhibitor of Stat3 that inhibits Stat3, Stat3 complex formation and Stat3-DNA binding activity in vitro (IC50 = 86 ± 33 µM) and Stat3-dependent transcriptional activities.

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 700.00
50 mg
¥ 1,750.00
100 mg
¥ 3,300.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

S3I-201 (NSC 74859) is a novel inhibitor of Stat3 that inhibits Stat3, Stat3 complex formation and Stat3-DNA binding activity in vitro (IC50 = 86 ± 33 µM) and Stat3-dependent transcriptional activities.
靶点信息
STAT3 (Cell-free assay)
86 μM
In vitro (25°C) DMSO 73 mg/mL (199.8 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 5% DMSO, 95% PEG 300 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.37 mL 136.84 mL 273.67 mL
0.5 mM 5.47 mL 27.37 mL 54.73 mL
1 mM 2.74 mL 13.68 mL 27.37 mL
5 mM 0.55 mL 2.74 mL 5.47 mL

*The above data is based on the productmolecular weight 365.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10817
MECHANISM OF ACTION Inhibitor
M. Wt 365.4
Formula C16H15NO7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 501919-59-1
Synonyms S3I201, NSC74859 , NSC-74859
SMILES CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O

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