S55746
目录号: A18361
BCL-2 抑制剂
S55746（BLC201）是一种强效的、口服活性的、选择性的BCL-2抑制剂，具有1.3 nM的Ki值和3.9 nM的Kd值。S55746（BLC201）具有抗肿瘤活性，并且毒性低。
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生物活性
| Discription | S55746 (BLC201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BLC201) has antitumor activity with low toxicity. | ||
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产品信息
| 目录号 | A18361 |
|---|---|
| 分子式 | C43H42N4O6 |
| 分子量 | 710.82 |
| CAS号 | 1448584-12-0 |
| SMILES | O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[C@H]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9 |
| 其他名称 | BLC201 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 88 mg/mL (123.8 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.07 mL | 70.34 mL | 140.68 mL |
| 0.5 mM | 2.81 mL | 14.07 mL | 28.14 mL |
| 1 mM | 1.41 mL | 7.03 mL | 14.07 mL |
| 5 mM | 0.28 mL | 1.41 mL | 2.81 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1448584-12-0 | 1448584-12-0 供应商 | 1448584-12-0 花费 | 1448584-12-0 生产商 | 订购 1448584-12-0 | 1448584-12-0 代理商