Sabatolimab (MBG453) is a high-affinity, humanized IgG4 (S228P) monoclonal antibody designed to specifically target TIM-3, an inhibitory receptor involved in the regulation of both adaptive and innate immune responses. This antibody serves as a potential agent for immunosuppression, targeting TIM-3 expressed on various immune and myeloid cells. Sabatolimab's specificity and mechanism of action make it a valuable tool for research in immune regulation and potential therapeutic applications in diseases characterized by immune dysregulation.
Sabatolimab (MBG453) is a high-affinity, humanized IgG4 (S228P) monoclonal antibody designed to specifically target TIM-3, an inhibitory receptor involved in the regulation of both adaptive and innate immune responses. This antibody serves as a potential agent for immunosuppression, targeting TIM-3 expressed on various immune and myeloid cells. Sabatolimab's specificity and mechanism of action make it a valuable tool for research in immune regulation and potential therapeutic applications in diseases characterized by immune dysregulation.
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