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SAG

促销

SMO 激动剂

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产品目录号: A13627

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SAG 2mg A13627-2
¥ 800.00
SAG 5mg A13627-5
¥ 1,400.00
SAG 10mg A13627-10
¥ 2,400.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SAG is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 uM).

SAG

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Chemical Information

目录号 A13627
Mechanism of action Agonist
分子量 490.1
化学分子式 C28H28ClN3OS
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 912545-86-9
Synonyms Smoothened Agonist
SMILES code CNC1CCC(CC1)N(CC2=CC=CC(=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl
化学名称 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide

生物活性

Description
SAG is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 uM).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.4 mL 102.02 mL 204.04mL
0.5 mM 4.08 mL 20.4 mL 40.81 mL
1 mM 2.04 mL 10.2 mL 20.4 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 490.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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