Salubrinal

目录号: A12676

eIF2α dephosphorylation inhibitor

Salubrinal Chemical Structure

CAS NO. 405060-95-9

Salubrinal is a cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC50 ~ 15 μM).

库存: 现货

规格 价格 数量
10 mg
¥ 1,000.00
25 mg
¥ 2,000.00
50 mg
¥ 3,500.00
100 mg
¥ 6,000.00
10mM * 1mL in DMSO
¥ 690.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Salubrinal is a cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC50 ~ 15 μM).
靶点信息
eIF2α (Cell-free assay)
In vitro DMSO 96 mg/mL (200.07 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.16 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 125.3 mL 626.49 mL 1252.98 mL
0.5 mM 25.06 mL 125.3 mL 250.6 mL
1 mM 12.53 mL 62.65 mL 125.3 mL
5 mM 2.51 mL 12.53 mL 25.06 mL

*The above data is based on the productmolecular weight 79.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12676
MECHANISM OF ACTION Inhibitor
M. Wt 79.81
Formula C21H17N4OSCl3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 405060-95-9
Synonyms N/A
SMILES C1=CC=C(C=C1)/C=C/C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3

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