SAR-20347

Name: SAR-20347
SKU: A20380
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A20380

TYK2/JAK1/JAK2/JAK3 抑制剂

SAR-20347 是一种抑制剂，针对 TYK2, JAK1, JAK2 和 JAK3，其半抑制浓度（IC50）分别为 0.6, 23, 26 和 41 纳摩尔（nM）。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥455.00	现货
10mg	¥770.00	现货
25mg	¥1,610.00	现货
50mg	¥2,555.00	现货
100mg	¥4,270.00	现货
200mg	¥5,985.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20380
分子式	C21H18ClFN4O4
分子量	444.84
CAS号	1450881-55-6
SMILES	O=C(C1=C(NC2=CC=C(C(N3CCOCC3)=O)C=C2)OC(C4=C(F)C=CC=C4Cl)=N1)N
其他名称	SAR20347, SAR 20347
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (173.09 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.48 mL	112.4 mL	224.8 mL
0.5 mM	4.5 mL	22.48 mL	44.96 mL
1 mM	2.25 mL	11.24 mL	22.48 mL
5 mM	0.45 mL	2.25 mL	4.5 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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