SAR-7334 HCl

Name: SAR-7334 HCl
SKU: A17237

目录号: A17237

TRPC6 inhibitor

SAR-7334 HCl Chemical Structure

CAS NO. 1333207-63-8

SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected.

库存：现货

规格	价格	数量
5 mg	￥ 2,070.00
10 mg	￥ 4,000.00
50 mg	￥ 7,200.00
100 mg	￥ 9,000.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.69 mL	113.43 mL	226.86 mL
0.5 mM	4.54 mL	22.69 mL	45.37 mL
1 mM	2.27 mL	11.34 mL	22.69 mL
5 mM	0.45 mL	2.27 mL	4.54 mL

*The above data is based on the productmolecular weight 440.793. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17237
作用机制	Inhibitor (抑制剂)
M. Wt	440.793
Formula	C21H24Cl3N3O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1333207-63-8
Synonyms	SAR-7334; SAR 7334; SAR7334
SMILES	N#CC1=CC=C(O[C@H]2[C@H](N3C[C@H](N)CCC3)CC4=C2C=CC=C4)C(Cl)=C1.[H]Cl.[H]Cl