SAR131675
目录号: A13377
VEGFR3 抑制剂
SAR131675,一种强效且选择性的 VEGFR-3-TK 抑制剂,具有抗淋巴管生成、抗肿瘤和抗转移活性。
Discription | SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. | |||||
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Targets |
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Cell Research |
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目录号 | A13377 |
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分子式 | C18H22N4O4 |
分子量 | 358.29 |
CAS号 | 1433953-83-3 |
SMILES | CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#C[C@](C)(COC)O)C(=O)NC)N |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 29 mg/mL (80.91 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 2 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 27.91 mL | 139.55 mL | 279.1 mL |
0.5 mM | 5.58 mL | 27.91 mL | 55.82 mL |
1 mM | 2.79 mL | 13.96 mL | 27.91 mL |
5 mM | 0.56 mL | 2.79 mL | 5.58 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2