SAR156497

目录号: A14382

Aurora Kinase inhibitor

SAR156497

SAR156497 Chemical Structure

CAS NO. 1256137-14-0

SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A), 1 nM (Aurora B / incenp), 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP3A4 and PDE3 inhibition.

库存: 缺货

规格 价格
5 mg
¥ 3,500.00
10 mg
¥ 6,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A), 1 nM (Aurora B / incenp), 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP3A4 and PDE3 inhibition.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.34 mL 106.72 mL 213.45 mL
0.5 mM 4.27 mL 21.34 mL 42.69 mL
1 mM 2.13 mL 10.67 mL 21.34 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14382
MECHANISM OF ACTION Inhibitor
M. Wt 468.5
Formula C27H24N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1256137-14-0
Synonyms SAR-156497, SAR 156497
SMILES O=C(C1=C2NC3=C(C(CCC3)=O)[C@@H](C4=CC=CC(OC5=NC6=CC=CC=C6N5)=C4)C2=CN1)OCC

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 SAR156497 | SAR156497 供应商 | 订购 SAR156497 | SAR156497 价格 | SAR156497 生产商 | 订单 SAR156497 | SAR156497 代理商 | 购买 1256137-14-0| 1256137-14-0 供应商 | 订购 1256137-14-0 | 1256137-14-0 价格 | 1256137-14-0 生产商 | 订单 1256137-14-0 | 1256137-14-0 代理商|buy SAR156497 | SAR156497 Supplier | purchase SAR156497 | SAR156497 cost | SAR156497 manufacturer | order SAR156497 | SAR156497 distributor | buy 1256137-14-0| 1256137-14-0 Supplier | purchase 1256137-14-0 | 1256137-14-0 cost | 1256137-14-0 manufacturer | order 1256137-14-0 | 1256137-14-0 distributor
Rewards