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SAR260301是有效的选择性I类磷脂酰肌醇3-激酶（PI3Kβ）β特异性抑制剂，该同工型的IC50为52 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.22 mL | 141.08 mL | 282.17 mL |
| 0.5 mM | 5.64 mL | 28.22 mL | 56.43 mL |
| 1 mM | 2.82 mL | 14.11 mL | 28.22 mL |
| 5 mM | 0.56 mL | 2.82 mL | 5.64 mL |
*The above data is based on the productmolecular weight 354.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16877 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 354.4 |
| Formula | C19H22N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1260612-13-2 |
| Synonyms | SAR 260301, SAR-260301 |
| SMILES | O=C1NC(CC(N2[C@@H](C)CC3=C2C=CC=C3)=O)=NC(N4CCOCC4)=C1 |
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