Saxagliptin (BMS-477118)

目录号: A11109

DPP-4 Inhibitor

Saxagliptin (BMS-477118) Chemical Structure

CAS NO. 361442-04-8

Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 1,500.00
50 mg
¥ 2,400.00
100 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 910.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.
Targets
DPP-4
26 nM
In vitro (25°C) DMSO 63 mg/mL (199.74 mM)
Water 63 mg/mL (199.74 mM)
Ethanol 24 mg/mL (76.09 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.71 mL 158.53 mL 317.06 mL
0.5 mM 6.34 mL 31.71 mL 63.41 mL
1 mM 3.17 mL 15.85 mL 31.71 mL
5 mM 0.63 mL 3.17 mL 6.34 mL

*The above data is based on the productmolecular weight 315.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11109
MECHANISM OF ACTION Inhibitor
M. Wt 315.4
Formula C18H25N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 361442-04-8
Synonyms BMS-477118,Onglyza
SMILES C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N

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