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Saxagliptin (BMS-477118)

Saxagliptin (BMS-477118)

Name: Saxagliptin (BMS-477118)
SKU: A11109

目录号: A11109

DPP-4 抑制剂

Product Citations (4)

Saxagliptin (BMS-477118) Chemical Structure

CAS NO. 361442-04-8

Saxagliptin (BMS-477118)是一种新型二肽基肽酶4（DPP-4）抑制剂，IC50为50 nM。

库存：现货

规格	价格	数量
10 mg	￥ 900.00
25 mg	￥ 1,500.00
50 mg	￥ 2,400.00
100 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 910.00

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生物活性

Saxagliptin (BMS-477118)是一种新型二肽基肽酶4（DPP-4）抑制剂，IC50为50 nM。

靶点信息

DPP-4
26 nM

溶解度 *

In vitro (25°C)	DMSO	62 mg/mL (196.57 mM)
	Water	62 mg/mL (196.57 mM)
	Ethanol	24 mg/mL (76.09 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.71 mL	158.53 mL	317.06 mL
0.5 mM	6.34 mL	31.71 mL	63.41 mL
1 mM	3.17 mL	15.85 mL	31.71 mL
5 mM	0.63 mL	3.17 mL	6.34 mL

*The above data is based on the productmolecular weight 315.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11109
作用机制	Inhibitor (抑制剂)
M. Wt	315.4
Formula	C18H25N3O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	361442-04-8
Synonyms	BMS-477118,Onglyza
SMILES	C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N