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SB 202190

促销

p38 MAPK 抑制剂

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产品目录号: A10823

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SB 202190 10mg A10823-10
¥ 400.00
SB 202190 50mg A10823-50
¥ 600.00
SB 202190 100mg A10823-100
¥ 800.00
SB 202190 200mg A10823-200
¥ 1,400.00
SB 202190 10mM * 1mL in DMSO A10823-10mM-D
¥ 500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase.

SB 202190

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 SB 202190 发表的文献 (2)
  • Tsai CC, .et al. Protease-activated receptor 2 induces migration and promotes Slug-mediated epithelial-mesenchymal transition in lung adenocarcinoma cells, Biochim Biophys Acta Mol Cell Res, 2018, Oct 13. pii: S0167-4889(18)30452-X PMID: 30321617
  • Jia-Shiuan Tsai, .et al. Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability, PLoS One, 2016, 11(1): e0147011 PMID: 26751215

Chemical Information

目录号 A10823
Mechanism of action Inhibitor
分子量 331.3
化学分子式 C20H14N3OF
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 152121-30-7
Synonyms SB-202190, SB202190
SMILES code C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
化学名称 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol

生物活性

Description
SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase.
Targets
p38α (Cell-free assay) p38β (Cell-free assay)
50 nM100 nM

溶解性

Solubility (25°C) * In vitro DMSO 66 mg/mL (199.19 mM)
Water <1 mg/mL (<1 mM)
Ethanol 12 mg/mL (36.21 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.18 mL 150.92 mL 301.84mL
0.5 mM 6.04 mL 30.18 mL 60.37 mL
1 mM 3.02 mL 15.09 mL 30.18 mL
5 mM 0.6 mL 3.02 mL 6.04 mL

*The above data is based on the productmolecular weight 331.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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