SB 203580

目录号: A10824

p38 MAPK inhibitor

SB 203580 Chemical Structure

CAS NO. 152121-47-6

SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.

库存: 现货

规格 价格 数量
25 mg
¥ 500.00
50 mg
¥ 800.00
100 mg
¥ 1,200.00
200 mg
¥ 2,300.00
10mM * 1mL in DMSO
¥ 670.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.
Targets
p38 MAPK (THP-1 cells) PKB (THP-1 cells)
0.3 μM-0.5 μM3 μM-5 μM
In vitro DMSO 43 mg/mL (113.92 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.5 mL 132.49 mL 264.97 mL
0.5 mM 5.3 mL 26.5 mL 52.99 mL
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL

*The above data is based on the productmolecular weight 377.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10824
MECHANISM OF ACTION Inhibitor
M. Wt 377.4
Formula C21H16FN3OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 152121-47-6
Synonyms SB-203580, SB203580
SMILES CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F

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