SB 216763

目录号: A10825

GSK-3 inhibitor

SB 216763 Chemical Structure

CAS NO. 280744-09-4

SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 600.00
50 mg
¥ 2,000.00
100 mg
¥ 3,400.00
10mM * 1mL in DMSO
¥ 650.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).
靶点信息
GSK-3α GSK-3β
34.3 nM~34.3 nM
In vitro (25°C) DMSO 23 mg/mL (61.95 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.94 mL 134.7 mL 269.4 mL
0.5 mM 5.39 mL 26.94 mL 53.88 mL
1 mM 2.69 mL 13.47 mL 26.94 mL
5 mM 0.54 mL 2.69 mL 5.39 mL

*The above data is based on the productmolecular weight 371.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10825
MECHANISM OF ACTION Inhibitor
M. Wt 371.2
Formula C19H12Cl2N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 280744-09-4
Synonyms SB-216763, SB216763
SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl

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