SB 216763

目录号: A10825

GSK-3 抑制剂

SB 216763

SB 216763 Chemical Structure

CAS NO. 280744-09-4

SB 216763是一种有效且具有选择性的细胞渗透性ATP竞争性GSK3α抑制剂,IC50值为34 nM(与GSK3β相似的效力)。

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 600.00
50 mg
¥ 2,000.00
100 mg
¥ 3,400.00
10mM * 1mL in DMSO
¥ 650.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SB 216763是一种有效且具有选择性的细胞渗透性ATP竞争性GSK3α抑制剂,IC50值为34 nM(与GSK3β相似的效力)。
靶点信息
GSK-3α GSK-3β
34.3 nM~34.3 nM
In vitro (25°C) DMSO 21 mg/mL (56.56 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.94 mL 134.7 mL 269.4 mL
0.5 mM 5.39 mL 26.94 mL 53.88 mL
1 mM 2.69 mL 13.47 mL 26.94 mL
5 mM 0.54 mL 2.69 mL 5.39 mL

*The above data is based on the productmolecular weight 371.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10825
作用机制 Inhibitor (抑制剂)
M. Wt 371.2
Formula C19H12Cl2N2O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 280744-09-4
Synonyms SB-216763, SB216763
SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl

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