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SB 218078

促销

Chk1 抑制剂

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产品目录号: A15480

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SB 218078 2mg A15480-2
¥ 1,000.00
SB 218078 5mg A15480-5
¥ 2,000.00
SB 218078 10mg A15480-10
¥ 3,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SB 218078 is an inhibitor of checkpoint kinase 1 (Chk1) that displays selectivity over other protein kinases (IC50 values are 15, 250 and 1000 nM for Chk1, cdc2 and PKC respectively)

SB 218078

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Chemical Information

目录号 A15480
Mechanism of action Inhibitor
分子量 393.39
化学分子式 C24H15N3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 135897-06-2
Synonyms SB218078, SB-218078
SMILES code C1CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C1O2)C7=C53)C(=O)NC6=O
化学名称 9,10,11,12,-Tetrahydro-9,12-epoxy-1H-diindolo(1,2,3-fg:3′,2′,1′-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2H)-dione

生物活性

Description
SB 218078 is an inhibitor of checkpoint kinase 1 (Chk1) that displays selectivity over other protein kinases (IC50 values are 15, 250 and 1000 nM for Chk1, cdc2 and PKC respectively)

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.42 mL 127.1 mL 254.2mL
0.5 mM 5.08 mL 25.42 mL 50.84 mL
1 mM 2.54 mL 12.71 mL 25.42 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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