微信关注
China
Total item
Cart Subtotal
￥ 0.00 产品详情
SB 239063是一种强效选择性p38 MAPKα/β抑制剂(p38α的IC50=44 nM)。SB 239063对ERK, JNK1和其他激酶的选择性超过220倍；比SB 203580的选择性高约3倍。SB 239063减少炎症细胞因子的产生，并在体内口服后具有神经保护作用。
靶点信息
| p38α | p38β | |||
| 44 nM | 44 nM |
| In vitro (25°C) | DMSO | 59 mg/mL (160.15 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 7 mg/mL (19 mM) | ||
| In vivo | 5% DMSO+30% PEG 300+ddH2O | 3 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.14 mL | 135.72 mL | 271.44 mL |
| 0.5 mM | 5.43 mL | 27.14 mL | 54.29 mL |
| 1 mM | 2.71 mL | 13.57 mL | 27.14 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.43 mL |
*The above data is based on the productmolecular weight 368.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11562 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 368.4 |
| Formula | C20H21FN4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 193551-21-2 |
| Synonyms | SB239063, SB-239063 |
| SMILES | COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
DBM 1285 dihydrochloride
DBM 1285 dihydrochloride是p38 MAPK抑制剂。在巨噬细胞和体内抑制p38磷酸化和LPS诱导的TNF-α产生。
TRC 051384
TRC 051384，属于取代的2-丙烯-1-酮类，是热休克蛋白70（HSP70）的有效诱导剂。HSP70的诱导是应激细胞的自然…
LY2228820 (Ralimetinib)
LY2228820 (Ralimetinib)是一种新型强效p38MAPK抑制剂，具有强效抗炎活性。
BMS-582949
BMS-582949是一种双重作用p38激酶抑制剂，非常适合于避免增加细胞p38活化的耐药机制。
Keywords:购买 SB 239063 | SB 239063 供应商 | 订购 SB 239063 | SB 239063 价格 | SB 239063 生产商 | 订单 SB 239063 | SB 239063 代理商 | 购买 193551-21-2| 193551-21-2 供应商 | 订购 193551-21-2 | 193551-21-2 价格 | 193551-21-2 生产商 | 订单 193551-21-2 | 193551-21-2 代理商|buy SB 239063 | SB 239063 Supplier | purchase SB 239063 | SB 239063 cost | SB 239063 manufacturer | order SB 239063 | SB 239063 distributor | buy 193551-21-2| 193551-21-2 Supplier | purchase 193551-21-2 | 193551-21-2 cost | 193551-21-2 manufacturer | order 193551-21-2 | 193551-21-2 distributor
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
ADOOQ 产品质量保证
We promise all products to perform as described.