SB-269970 hydrochloride
目录号: A21889
5-HT7 receptor 拮抗剂
SB269970 盐酸盐(SB-269970A)是 SB-269970 的盐酸盐形式,它是一种 5-HT7 受体拮抗剂,具有 pKi 值为 8.3,对其他受体的选择性超过 50 倍。
Discription | SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors. | ||
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目录号 | A21889 |
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分子式 | C18H29ClN2O3S |
分子量 | 388.95 |
CAS号 | 261901-57-9 |
SMILES | OC1=CC=CC(S(=O)(N2[C@@H](CCN3CCC(C)CC3)CCC2)=O)=C1.[H]Cl |
其他名称 | SB-269970A, SB269970, SB 269970 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 11 mg/mL (28.28 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.71 mL | 128.55 mL | 257.1 mL |
0.5 mM | 5.14 mL | 25.71 mL | 51.42 mL |
1 mM | 2.57 mL | 12.86 mL | 25.71 mL |
5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2