SB-334867 free base
目录号: A16695
orexin OX1 receptor 拮抗剂
SB-334867 free base 是一种选择性的非肽类orexin OX1受体拮抗剂,具有 pKb 值为 7.2。
| Discription | SB-334867 free base is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2. | ||
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| Targets |
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| 目录号 | A16695 |
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| 分子式 | C17H13N5O2 |
| 分子量 | 319.32 |
| CAS号 | 792173-99-0 |
| SMILES | O=C(NC1=CC(OC(C)=N2)=C2C=C1)NC3=CC=NC4=CC=CN=C43 |
| 其他名称 | SB334867A free base |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 59 mg/mL (184.76 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 3 mg/mL (9.39 mM) | ||
| In vivo | 1% CMC Na | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.32 mL | 156.58 mL | 313.17 mL |
| 0.5 mM | 6.26 mL | 31.32 mL | 62.63 mL |
| 1 mM | 3.13 mL | 15.66 mL | 31.32 mL |
| 5 mM | 0.63 mL | 3.13 mL | 6.26 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2