SB 334867

目录号: A12786

OX1 receptor antagonist

SB 334867

SB 334867 Chemical Structure

CAS NO. 249889-64-3

SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 750.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.32 mL 156.58 mL 313.17 mL
0.5 mM 6.26 mL 31.32 mL 62.63 mL
1 mM 3.13 mL 15.66 mL 31.32 mL
5 mM 0.63 mL 3.13 mL 6.26 mL

*The above data is based on the productmolecular weight 319.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A12786
MECHANISM OF ACTION Antagonist
M. Wt 319.32
Formula C17H13N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 249889-64-3
Synonyms SB334867,SB-334867
SMILES CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4

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