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SB 399885 HCl

促销

5-HT6 拮抗剂

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产品目录号: A14102

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SB 399885 HCl 10mg A14102-10
¥ 1,200.00
SB 399885 HCl 25mg A14102-25
¥ 2,500.00
SB 399885 HCl 50mg A14102-50
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SB 399885 hydrochloride is a potent, brain penetrant, and orally active SR-6 antagonist. It displays > 200-fold selectivity for SR-6 over other serotonin receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human SR-6 receptors, respectively).

SB 399885 HCl

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Chemical Information

目录号 A14102
Mechanism of action Antagonist
分子量 446.353
化学分子式 C18H21Cl2N3O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 402713-80-8
Synonyms SB399885, SB-399885
SMILES code COC1=C(C=C(C=C1)S(=O)(=O)NC2=CC(=CC(=C2OC)Cl)Cl)N3CCNCC3.Cl
化学名称 N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride

生物活性

Description
SB 399885 hydrochloride is a potent, brain penetrant, and orally active SR-6 antagonist. It displays > 200-fold selectivity for SR-6 over other serotonin receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human SR-6 receptors, respectively).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.4 mL 112.02 mL 224.04mL
0.5 mM 4.48 mL 22.4 mL 44.81 mL
1 mM 2.24 mL 11.2 mL 22.4 mL
5 mM 0.45 mL 2.24 mL 4.48 mL

*The above data is based on the productmolecular weight 446.353. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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